Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.80 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15319505 | 0.94 | HCAR3 (0.68) | ALOX15HCAR3KMT2AALDH1A1MAPT | |
| SCHEMBL15320045 | 0.94 | HCAR3 (0.68) | ALOX15HCAR3KMT2AALDH1A1MAPT | |
| SCHEMBL15320956 | 0.94 | HCAR3 (0.68) | ALOX15HCAR3KMT2AALDH1A1MAPT | |
| SCHEMBL2027705 | 0.94 | HCAR3 (0.68) | ALOX15HCAR3KMT2AALDH1A1MAPT | |
| SCHEMBL15319810 | 0.93 | HCAR3 (0.70) | ALOX15HCAR3KMT2AALDH1A1MAPT | |
| SCHEMBL15320365 | 0.91 | HCAR3 (0.70) | ALOX15HCAR3KMT2AALDH1A1MAPT | |
| SCHEMBL31385531 | 0.89 | ALOX15 (1.00) | ALOX15ALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL15320214 | 0.89 | ALOX15 (1.00) | ALOX15ALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL15319744 | 0.89 | ALOX15 (1.00) | ALOX15ALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL2032512 | 0.89 | ALOX15 (1.00) | ALOX15ALDH1A1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1162196-A1 | FUSED-RING COMPOUNDS AND USE THEREOF AS DRUGS | JAPAN TOBACCO INC. (JP) | 2001-12-12 | — | — | EP | disclosed |