Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 2/20 | 1.00 |
| ▸ | CRHR2 | Q13324 | 2/20 | 1.00 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.68 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.68 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.68 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21345872 | 0.87 | CRHBP (0.76) | CRHBPCRHR2AKR1C2AKR1C1AKR1C3 | |
| SCHEMBL581997 | 0.84 | CRHBP (0.70) | CRHBPCRHR2AKR1C2AKR1C1AKR1C3 | |
| SCHEMBL18319714 | 0.82 | AKR1C2 (1.00) | CRHBPCRHR2AKR1C2AKR1C1AKR1C3 | |
| SCHEMBL11778374 | 0.82 | CRHBP (0.68) | CRHBPCRHR2AKR1C2AKR1C1AKR1C3 | |
| SCHEMBL9512827 | 0.80 | CRHBP (0.66) | CRHBPCRHR2AKR1C2AKR1C1AKR1C3 | |
| SCHEMBL6346254 | 0.80 | CRHBP (0.66) | CRHBPCRHR2AKR1C2AKR1C1AKR1C3 | |
| SCHEMBL7334496 | 0.80 | CRHBP (0.67) | CRHBPCRHR2AKR1C2AKR1C1AKR1C3 | |
| SCHEMBL29662848 | 0.79 | APEX1 (0.67) | CRHBPCRHR2AKR1C2AKR1C1AKR1C3 | |
| SCHEMBL5306730 | 0.79 | AKR1C2 (0.75) | CRHBPCRHR2AKR1C2AKR1C1AKR1C3 | |
| SCHEMBL22717286 | 0.77 | CRHBP (0.62) | CRHBPCRHR2AKR1C2AKR1C1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11197854-B1 | Inhibitors for targeting flaviviruses | NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC (US) | 2021-12-14 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| WO-2018204764-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION (US) | 2018-11-08 | — | — | WO | disclosed |
| EP-1077967-A2 | BIPHENYL OXO-ACETIC ACIDS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058518-A2 | BIPHENYL OXO-ACETIC ACIDS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-18 | — | — | WO | disclosed |
| US-4170614-A | HYDROLYSIS OF TRIS(2,6-DIHALOPHENYL) PHOSPHATE | PPG INDUSTRIES, INC. (US) | 1979-10-09 | — | — | US | disclosed |
| US-4059655-A | REACTING A 2,6-DIHALOPHENOL WITH PHOSPHORUS OXYHALIDE, HYDROLYSIS | PPG INDUSTRIES, INC. (US) | 1977-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11197854-B1 | Inhibitors for targeting flaviviruses | HAVCR2, MME, SPINT2 | CRHBP 1000/4885CRHR2 4705/4885AKR1C2 4678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.