Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.70 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578252 | 0.84 | TTR (0.70) | CRHBPCRHR2CYP3A4TSHRTDP1 | |
| SCHEMBL7334496 | 0.84 | CRHBP (0.67) | CRHBPCRHR2CYP3A4TSHRTDP1 | |
| SCHEMBL7842844 | 0.84 | CRHBP (1.00) | CRHBPCRHR2CYP3A4TSHRTDP1 | |
| SCHEMBL18893094 | 0.80 | CRHBP (0.50) | CRHBPCRHR2CYP3A4TSHRTDP1 | |
| SCHEMBL9579828 | 0.80 | CRHBP (0.61) | CRHBPCRHR2CYP3A4TSHRTDP1 | |
| SCHEMBL9615644 | 0.80 | CA1 (0.65) | CRHBPCRHR2CYP3A4TSHRTDP1 | |
| SCHEMBL18224 | 0.79 | CYP3A4 (1.00) | CRHBPCRHR2CYP3A4TSHRTDP1 | |
| SCHEMBL69980 | 0.79 | CYP3A4 (0.65) | CRHBPCRHR2CYP3A4TSHRTDP1 | |
| Methane SCHEMBL9716111 | 0.76 | CYP3A4 (0.61) | CRHBPCRHR2CYP3A4TSHRTDP1 | |
| SCHEMBL10546483 | 0.76 | CYP3A4 (0.93) | CRHBPCRHR2CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576739-B2 | Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups | GENERAL ELECTRIC COMPANY | 2003-06-10 | — | — | US | claimed |
| WO-2001085825-A2 | METHOD OF POLYCARBONATE PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2001-11-15 | — | — | WO | claimed |
| US-20250034071-A1 | (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2025-01-30 | — | — | US | disclosed |
| US-20250019332-A1 | (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS | REUTER CHEMISCHE APPBAU E K (DE) | 2025-01-16 | — | — | US | disclosed |
| EP-1307499-B2 | CONTINUOUS PREPARATION OF POLYCARBONATE | GEN ELECTRIC (US) | 2012-02-15 | — | — | EP | disclosed |
| US-20100199491-A1 | MANUFACTURING METHOD OF IMAGE PICK-UP DEVICE, IMAGE PICK-UP DEVICE AND OPTICAL ELEMENT | KONICA MINOLTA OPTO, INC. (JP) | 2010-08-12 | — | — | US | disclosed |
| EP-2166395-A1 | IMAGING DEVICE MANUFACTURING METHOD, IMAGING DEVICE AND OPTICAL ELEMENT | Konica Minolta Opto, Inc. (JP) | 2010-03-24 | — | — | EP | disclosed |
| US-20080318108-A1 | Solid Electrolyte, Membrane and Electrode Assembly, and Fuel Cell | FUJIFILM CORPORATION | 2008-12-25 | — | — | US | disclosed |
| US-7442459-B2 | Solid electrolyte, membrane and electrode assembly, and fuel cell | FUJIFILM CORPORATION (JP) | 2008-10-28 | — | — | US | disclosed |
| US-20070264551-A1 | Membrane/Electrode Assembly and Fuel Cell | FUJIFILM CORPORATION (JP) | 2007-11-15 | — | — | US | disclosed |
| US-20070231671-A1 | Catalyst Material For Use In Fuel Cell, Catalyst Membrane, Membrane Electrode Assembly and Fuel Cell | FUJIFILM CORPORATION | 2007-10-04 | — | — | US | disclosed |
| US-4168368-A | STRESS RESISTANCE | THE DOW CHEMICAL COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4156769-A | Process for making polycarbonates using 1,1-dimethyl urea compounds as the catalysts | THE DOW CHEMICAL COMPANY (US) | 1979-05-29 | — | — | US | disclosed |
| US-4096341-A | MONOMERS FOR POLYESTERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-06-20 | — | — | US | disclosed |
| US-4085091-A | Thermally stable, rigid polyesters from thermally stable, rigid dibasic acids and aromatic dihydroxy compounds | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
| US-4059566-A | Process for controlling the molecular weight of polycarbonates using ammonia or ammonia compounds | THE DOW CHEMICAL COMPANY (US) | 1977-11-22 | — | — | US | disclosed |
| US-4055544-A | Process for making polycarbonates using ammonia or ammonia compounds as the catalysts | THE DOW CHEMICAL COMPANY (US) | 1977-10-25 | — | — | US | disclosed |
| US-4020045-A | METALLIC SULFITES | THE DOW CHEMICAL COMPANY (US) | 1977-04-26 | — | — | US | disclosed |
| US-3992357-A | THERMOPLASTIC | THE DOW CHEMICAL COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3956510-A | NESTING, CYLINDERS, LOOPS | BEALL NELSON J | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250019332-A1 | (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS | CBR1, CBR3, CBX2 | CRHBP 3535/4885CRHR2 319/4885CYP3A4 259/4885 |
| US-20250034071-A1 | (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS | CBR1, CBR3, AHR | CRHBP 3232/4885CRHR2 432/4885CYP3A4 165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.