Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6721441 | 0.91 | SMN1; SMN2 (0.34) | SMN1; SMN2RAB9AMEN1HPGDKMT2A | |
| SCHEMBL6728637 | 0.87 | SPR (0.31) | — | |
| SCHEMBL6732599 | 0.81 | SMN1; SMN2 (0.35) | SMN1; SMN2RAB9AMEN1HPGDKMT2A | |
| SCHEMBL8135585 | 0.80 | RAB9A (0.35) | SMN1; SMN2RAB9ALMNANR3C1PGR | |
| SCHEMBL8459595 | 0.79 | RAB9A (0.32) | SMN1; SMN2RAB9AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL8014294 | 0.79 | RAB9A (0.32) | SMN1; SMN2RAB9AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL8014291 | 0.79 | RAB9A (0.32) | SMN1; SMN2RAB9AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL6721484 | 0.78 | SPR (0.31) | — | |
| SCHEMBL6732608 | 0.77 | — | — | |
| SCHEMBL8522701 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712853-B1 | PYRAZOLE DERIVATIVE | IDEMITSU KOSAN CO (JP) | 2001-02-28 | — | — | EP | disclosed |
| EP-0712853-A1 | PYRAZOLE DERIVATIVE | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1996-05-22 | — | — | EP | disclosed |