Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9406514 | 0.94 | AGTR1 (0.70) | AGTR1AGTR2 | |
| SCHEMBL9854401 | 0.92 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9705276 | 0.89 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL29486817 | 0.88 | AGTR1 (0.72) | AGTR1AGTR2 | |
| SCHEMBL9853668 | 0.88 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL7622112 | 0.88 | AGTR1 (0.72) | AGTR1AGTR2 | |
| SCHEMBL12971985 | 0.88 | AGTR1 (0.51) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL7841670 | 0.87 | AGTR1 (0.71) | AGTR1AGTR2 | |
| SCHEMBL9054179 | 0.87 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9851502 | 0.87 | AGTR1 (0.50) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399731-B2 | Azaindenes | ASTRAZENECA AB (SE) | 2001-07-11 | — | — | EP | claimed |
| EP-0399731-B1 | Azaindenes | ZENECA LTD (GB) | 1993-12-08 | — | — | EP | claimed |
| US-5334718-A | Decyclizing a phenyl or a pyridyl or pyrimidyl group by reacting with a base to get angiotension antagonist | ZENECA LIMITED (GB) | 1994-08-02 | — | — | US | disclosed |
| EP-0554098-A2 | Process for the preparation of imidazo 4,5-b pyridine derivatives | ZENECA LIMITED (GB) | 1993-08-04 | — | — | EP | disclosed |