Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7841358 | 0.88 | GNRHR (0.46) | GNRHR | |
| SCHEMBL7852099 | 0.82 | GNRHR (0.52) | GNRHR | |
| SCHEMBL7850711 | 0.81 | GNRHR (0.50) | GNRHR | |
| SCHEMBL7857100 | 0.81 | GNRHR (0.55) | GNRHR | |
| SCHEMBL7855497 | 0.79 | GNRHR (0.45) | GNRHR | |
| SCHEMBL7851919 | 0.76 | MAPT (0.43) | GNRHR | |
| SCHEMBL7852573 | 0.76 | MEN1 (0.41) | GNRHR | |
| SCHEMBL7842941 | 0.76 | CYP1A2 (0.47) | — | |
| SCHEMBL7851615 | 0.76 | MAPT (0.43) | GNRHR | |
| SCHEMBL7841825 | 0.74 | GNRHR (0.51) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640606-B1 | Thienopyrimidine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-07 | — | — | EP | disclosed |
| US-6140325-A | HAS ENDOTHELIN ANTAGONISTIC ACTION; FOR TREATING LIVER HYPOFUNCTION, ACUTE RENAL INSUFFICIENCY, CARDIAC INFARCTION OR LIVER INSUFFICIENCY, VASOCONSTRICTION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-10-31 | — | — | US | disclosed |
| EP-0640606-A1 | Thienopyrimidine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-03-01 | — | — | EP | disclosed |