Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.55 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30743451 | 0.88 | GPR119 (0.43) | CHRNB2CHRNA4GPR119ALOX5APFEN1 | |
| SCHEMBL7410033 | 0.88 | GPR119 (0.43) | CHRNB2CHRNA4GPR119ALOX5APFEN1 | |
| SCHEMBL29508261 | 0.88 | GPR119 (0.43) | CHRNB2CHRNA4GPR119ALOX5APFEN1 | |
| SCHEMBL23605880 | 0.88 | GPR119 (0.43) | CHRNB2CHRNA4GPR119ALOX5APFEN1 | |
| SCHEMBL29529911 | 0.88 | GPR119 (0.43) | CHRNB2CHRNA4GPR119ALOX5APFEN1 | |
| SCHEMBL24399166 | 0.88 | GPR119 (0.43) | CHRNB2CHRNA4GPR119ALOX5APFEN1 | |
| SCHEMBL22596603 | 0.86 | GPR119 (0.48) | CHRNB2CHRNA4GPR119ALOX5APFEN1 | |
| SCHEMBL22596423 | 0.86 | GPR119 (0.43) | CHRNB2CHRNA4GPR119ALOX5APFEN1 | |
| SCHEMBL22596513 | 0.86 | GPR119 (0.43) | CHRNB2CHRNA4GPR119ALOX5APFEN1 | |
| SCHEMBL22596320 | 0.86 | GPR119 (0.48) | CHRNB2CHRNA4GPR119ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663912-B1 | HETEROCYCLIC ETHER COMPOUNDS THAT ENHANCE COGNITIVE FUNCTION | ABBOTT LAB (US) | 2001-12-12 | — | — | EP | disclosed |