SCHEMBL7410033

SCHEMBL7410033

CC(C)(C)OC(=O)N1CC[C@@H]1COc1cnccc1Cl

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 9/20 0.43
ALOX5AP P20292 1/20 0.41
FEN1 P39748 1/20 0.41
CHRNB2 P17787 1/20 0.41
CHRNA4 P43681 1/20 0.41
CHRNB4 P30926 1/20 0.40
CHRNA3 P32297 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7843338 0.88 CHRNB2 (0.55) GPR119ALOX5APFEN1CHRNB2CHRNA4
SCHEMBL23605880 0.87 GPR119 (0.43) GPR119ALOX5APFEN1CHRNB2CHRNA4
SCHEMBL29529911 0.87 GPR119 (0.43) GPR119ALOX5APFEN1CHRNB2CHRNA4
SCHEMBL24399166 0.87 GPR119 (0.43) GPR119ALOX5APFEN1CHRNB2CHRNA4
SCHEMBL29508261 0.87 GPR119 (0.43) GPR119ALOX5APFEN1CHRNB2CHRNA4
SCHEMBL30743451 0.87 GPR119 (0.43) GPR119ALOX5APFEN1CHRNB2CHRNA4
SCHEMBL22596423 0.85 GPR119 (0.43) GPR119ALOX5APFEN1CHRNB2CHRNA4
SCHEMBL22596603 0.85 GPR119 (0.48) GPR119ALOX5APFEN1CHRNB2CHRNA4
SCHEMBL22596320 0.85 GPR119 (0.48) GPR119ALOX5APFEN1CHRNB2CHRNA4
SCHEMBL22596513 0.85 GPR119 (0.43) GPR119ALOX5APFEN1CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1047690-A1 HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION Abbott Laboratories (US) 2000-11-02 EP disclosed
WO-1999032480-A1 HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION ABBOTT LABORATORIES (US) 1999-07-01 WO disclosed