Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | VIP | P01282 | 1/20 | 0.43 |
| ▸ | KCNA6 | P17658 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24080898 | 0.87 | CREBBP (0.51) | CREBBPPKMDAOHRH3ADRA2A | |
| SCHEMBL7845382 | 0.83 | PKM (0.60) | CREBBPPKMDAOHRH3ADRA2A | |
| SCHEMBL23330945 | 0.80 | CREBBP (0.51) | CREBBPPKMDAOALDH1A1MAPT | |
| SCHEMBL7845571 | 0.75 | MAPT (0.46) | ALDH1A1MAPTSMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL7849073 | 0.74 | HDAC3 (0.55) | — | |
| SCHEMBL28746425 | 0.74 | CREBBP (0.60) | CREBBPPKMDAOHRH3ADRA2A | |
| SCHEMBL13486629 | 0.73 | HRH3 (0.72) | PKMHRH3ADRA2AADRA1DALDH1A1 | |
| SCHEMBL13655571 | 0.72 | PKM (0.51) | CREBBPPKMDAOHRH3ADRA2A | |
| SCHEMBL23952430 | 0.72 | CREBBP (0.67) | CREBBPPKMDAOHRH3ADRA2A | |
| SCHEMBL23718091 | 0.72 | CREBBP (1.00) | CREBBPPKMDAOHRH3ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711773-B1 | HYMENIALDISINE AND DERIVATIVE THEREOF, PROCESS FOR PRODUCING INTERMEDIATE FOR SYNTHESIZING THE SAME, AND SAID INTERMEDIATE | SUNTORY LTD (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5621099-A | CARDIOVASCULAR DISORDERS | SUNTORY LIMITED (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0711773-A1 | HYMENIALDISINE AND DERIVATIVE THEREOF, PROCESS FOR PRODUCING INTERMEDIATE FOR SYNTHESIZING THE SAME, AND SAID INTERMEDIATE | SUNTORY LIMITED (JP) | 1996-05-15 | — | — | EP | disclosed |