Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 6/20 | 0.35 |
| ▸ | CDK2 | P24941 | 6/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | ATP4A | P20648 | 2/20 | 0.32 |
| ▸ | ATP4B | P51164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 2/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | PLK1 | P53350 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7229276 | 0.87 | NOS3 (0.42) | CCR1CCR5CCR8PLAUNOS3 | |
| Hydrochloric Acid SCHEMBL7231887 | 0.86 | NOS3 (0.42) | CCR1CCR5CCR8PLAUNOS3 | |
| Hydrochloric Acid SCHEMBL7238267 | 0.81 | CCR1 (0.38) | CCR1CCR5CCR8PLAUCDK4 | |
| SCHEMBL7238645 | 0.80 | SMN1; SMN2 (0.37) | CCR1CCR5CCR8PLAUCDK4 | |
| SCHEMBL7239613 | 0.79 | SMN1; SMN2 (0.46) | CCR1CCR5CCR8CDK4CDK2 | |
| SCHEMBL925682 | 0.72 | CCR1 (0.52) | CCR1CCR5CCR8CDK4CDK2 | |
| SCHEMBL7229862 | 0.72 | CCR1 (0.41) | CCR1CCR5CCR8CDK4CDK2 | |
| SCHEMBL7229860 | 0.72 | CCR1 (0.41) | CCR1CCR5CCR8CDK4CDK2 | |
| SCHEMBL7229076 | 0.70 | PIK3CA (0.40) | CCR1CCR5CCR8NR2F2MAPT | |
| SCHEMBL7240097 | 0.70 | PIK3CA (0.40) | CCR1CCR5CCR8NR2F2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157022-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000049015-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-24 | — | — | WO | disclosed |