Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7852208 | 0.88 | HDAC1 (0.43) | HDAC1HDAC2NPC1RAB9APOLB | |
| SCHEMBL3818243 | 0.88 | RAB9A (0.41) | SCDSMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL14477481 | 0.84 | RAB9A (0.46) | SMN1; SMN2NPC1RAB9AYTHDC1P2RX7 | |
| SCHEMBL14309812 | 0.83 | TSHR (0.43) | SMN1; SMN2HDAC1HDAC2NPC1RAB9A | |
| SCHEMBL5048124 | 0.80 | MAP3K5 (0.40) | SCDSMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL434582 | 0.79 | CDK1 (0.43) | HDAC1HDAC2NPC1RAB9APOLB | |
| SCHEMBL8538543 | 0.79 | HDAC1 (0.52) | HDAC1HDAC2YTHDC1P2RX7 | |
| SCHEMBL10077237 | 0.78 | RAB9A (0.40) | SCDNPC1RAB9APOLB | |
| SCHEMBL3139870 | 0.78 | MEN1 (0.48) | — | |
| SCHEMBL3130095 | 0.78 | TDP1 (0.48) | SMN1; SMN2HDAC1HDAC2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1085020-A1 | Synthesis of modified diaminopurines and their incorporation into oligomers | DAKO A/S (DK) | 2001-03-21 | — | — | EP | disclosed |