Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FSHR | P23945 | 1/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5051783 | 0.94 | MAP3K5 (0.40) | MAP3K5SMN1; SMN2SCDACHENPC1 | |
| SCHEMBL5050469 | 0.92 | TRPV1 (0.41) | MAP3K5SMN1; SMN2SCDACHENPC1 | |
| SCHEMBL5048107 | 0.87 | ACHE (0.38) | SMN1; SMN2ACHENPC1KDM4EMAPT | |
| SCHEMBL7617736 | 0.87 | SMN1; SMN2 (0.37) | SMN1; SMN2ACHENPC1POLBKDM4E | |
| SCHEMBL5045348 | 0.85 | ACHE (0.37) | ACHENPC1KDM4EMAPTTDP1 | |
| SCHEMBL7843904 | 0.80 | SCD (0.43) | SMN1; SMN2SCDACHENPC1RAB9A | |
| SCHEMBL9079905 | 0.79 | MEN1 (0.42) | MAP3K5SMN1; SMN2SCDACHEPTGER1 | |
| SCHEMBL7617492 | 0.79 | HDAC1 (0.45) | POLBKDM4EMAPTTDP1 | |
| SCHEMBL14309812 | 0.74 | TSHR (0.43) | SMN1; SMN2ACHENPC1RAB9APOLB | |
| SCHEMBL14477481 | 0.73 | RAB9A (0.46) | SMN1; SMN2ACHENPC1RAB9APTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1873156-A1 | Process for the preparation of 6-[[(alkoxy)carbonyl]amino]-9H-Purine-9-acetic acid and 4-[(alkoxycarbonyl)amino]-2-oxo-1(2H)-Pyrimidineacetic acid derivatives as synthons for the synthesis of peptide nucleic acids | PerSeptive Biosystems, Inc. (US) | 2008-01-02 | — | — | EP | disclosed |
| EP-0736027-B1 | GUANINE SYNTHONS FOR PEPTIDE NUCLEIC ACID SYNTHESIS AND METHOD FOR PRODUCTION | PERSEPTIVE BIOSYSTEMS INC (US) | 2002-05-29 | — | — | EP | disclosed |