Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2627311 | 0.82 | NPC1 (0.50) | ALDH1A1KMT2ALMNAMAPTNOTUM | |
| SCHEMBL19814412 | 0.82 | NOTUM (0.53) | ALDH1A1KMT2ALMNAMAPTNOTUM | |
| SCHEMBL19817400 | 0.82 | NOTUM (0.37) | ALDH1A1KMT2ALMNAMAPTNOTUM | |
| SCHEMBL1353531 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KMT2ALMNAHIF1AMAPT | |
| SCHEMBL31284235 | 0.79 | CYP3A4 (0.49) | ALDH1A1KMT2ALMNANOTUMMEN1 | |
| SCHEMBL22636656 | 0.79 | LMNA (0.61) | ALDH1A1KMT2ALMNAHIF1AMAPT | |
| SCHEMBL19814257 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KMT2ALMNAMAPTNOTUM | |
| SCHEMBL1040770 | 0.79 | LMNA (0.54) | ALDH1A1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL14548862 | 0.76 | LMNA (0.47) | ALDH1A1KMT2ALMNAMAPTNOTUM | |
| SCHEMBL2627234 | 0.76 | LMNA (0.40) | ALDH1A1KMT2ALMNAMAPTNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1075073-C | Hetero-aromatic ring substituted phenyloxazolidinone antimicrobials | UPJOHN CO (US) | 2001-11-21 | — | — | CN | disclosed |
| EP-0807112-B1 | HETERO-AROMATIC RING SUBSTITUTED PHENYLOXAZOLIDINONE ANTIMICROBIALS | UPJOHN CO (US) | 2001-09-05 | — | — | EP | disclosed |
| US-6124334-A | A BACTERICIDE TREATING INFECTIONS CAUSED BY GRAM-POSITIVE AEROBIC BACTERIA SUCH AS STAPHYLOCOCCUS, STREPTOCOCCUS AND ENTEROCOCCUS AS WELL AS ANAEROBIC ORGANISMS SUCH AS BACTEROIDES AND CLOSTRIDIUM AND MYCOBACTERIDIUM | PHARMACIA & UPJOHN COMPANY (US) | 2000-09-26 | — | — | US | disclosed |
| US-5910504-A | BACTERICIDES TREATING INFECTIONS | PHARMACIA & UPJOHN (US) | 1999-06-08 | — | — | US | disclosed |
| CN-1172484-A | Phenyl oxazolidinone antibacterial agents substituted with heteroaromatic rings | UPJOHN CO (US) | 1998-02-04 | — | — | CN | disclosed |
| EP-0807112-A1 | HETERO-AROMATIC RING SUBSTITUTED PHENYLOXAZOLIDINONE ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996023788-A1 | HETERO-AROMATIC RING SUBSTITUTED PHENYLOXAZOLIDINONE ANTIMICROBIALS | PHARMACIA + UPJOHN COMPANY (US) | 1996-08-08 | — | — | WO | disclosed |