SCHEMBL7843935

SCHEMBL7843935

Cc1cc2c(cc1Br)C(C)(C)OC2(C)C

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.37
CES1 P23141 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15428014 0.85 AHR (0.35)
SCHEMBL6027545 0.77 RXRA (0.32) BCHECES1
SCHEMBL15427993 0.76 POLB (0.33)
SCHEMBL4711277 0.74 BCHE (0.38) BCHECES1
SCHEMBL21238596 0.73 BCHE (0.37) BCHECES1
SCHEMBL3170254 0.73 RXRA (0.44)
SCHEMBL4760312 0.72 BCHE (0.34) BCHECES1
SCHEMBL4709163 0.71 BCHE (0.36) BCHECES1
SCHEMBL14159910 0.71 BCHE (0.36) BCHECES1
SCHEMBL4709608 0.71 BCHE (0.36) BCHECES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1320599-A Limited 9-cis-isotretinoins AMERICAN CYANAMID CO (US) 2001-11-07 CN disclosed
EP-0718285-B1 Restricted 9-cis-retinoids AMERICAN CYANAMID CO (US) 2001-04-11 EP disclosed
EP-0997455-A1 Restricted 9-cis retenoids American Cyanamid Company (US) 2000-05-03 EP disclosed
US-5968908-A Restricted 9-cis retinoids AMERICAN CYANAMID COMPANY (US) 1999-10-19 US disclosed
CN-1176248-A Restricted 9-CIS-retinoids AMERICAN CYANAMID CO (US) 1998-03-18 CN disclosed
EP-0718285-A2 Restricted 9-cis-retinoids American Cyanamid Company (US) 1996-06-26 EP disclosed