Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848837 | 0.86 | TP53 (0.39) | TP53CNR2AKR1B1HCRTR2KMT2A | |
| SCHEMBL6087401 | 0.85 | HCRTR2 (0.38) | TP53CNR2HCRTR2KMT2AMEN1 | |
| SCHEMBL7837569 | 0.81 | KMT2A (0.37) | CNR2AKR1B1HCRTR2KMT2AMEN1 | |
| SCHEMBL7846207 | 0.81 | TLR7 (0.42) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7847395 | 0.81 | MEN1 (0.39) | TP53AKR1B1HCRTR2KMT2AMEN1 | |
| SCHEMBL7848304 | 0.79 | TLR7 (0.33) | KMT2AMEN1MAPTALDH1A1TLR7 | |
| SCHEMBL7847101 | 0.78 | GRIN1 (0.45) | GABRA1GABRA5ALDH1A1TLR7 | |
| SCHEMBL7848800 | 0.78 | KDM4E (0.34) | KMT2AMEN1MAPTRAB9ALMNA | |
| SCHEMBL6087657 | 0.77 | TP53 (0.39) | TP53CNR2HCRTR2KMT2AMEN1 | |
| SCHEMBL7849498 | 0.76 | TLR7 (0.33) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |