Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836075 | 0.86 | RAB9A (0.38) | KMT2AMEN1AKR1B1HCRTR2RAB9A | |
| SCHEMBL6086306 | 0.85 | KMT2A (0.39) | KMT2AMEN1AKR1B1HCRTR2RAB9A | |
| SCHEMBL7844185 | 0.81 | TP53 (0.37) | KMT2AMEN1AKR1B1HCRTR2RAB9A | |
| SCHEMBL7843371 | 0.81 | ALDH1A1 (0.41) | KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL7847395 | 0.81 | MEN1 (0.39) | KMT2AMEN1AKR1B1HCRTR2RAB9A | |
| SCHEMBL7845199 | 0.78 | GRIN1 (0.45) | ALDH1A1GABRA1GABRA5 | |
| SCHEMBL6089793 | 0.77 | RAB9A (0.38) | KMT2AMEN1AKR1B1HCRTR2RAB9A | |
| SCHEMBL7848697 | 0.76 | TLR7 (0.32) | KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL6087401 | 0.76 | HCRTR2 (0.38) | KMT2AMEN1HCRTR2RAB9APIK3CB | |
| SCHEMBL6087446 | 0.75 | HCRTR2 (0.39) | KMT2AMEN1AKR1B1HCRTR2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |