Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6087657 | 0.86 | TP53 (0.39) | HCRTR2TP53CNR2MAPTALDH1A1 | |
| SCHEMBL7844185 | 0.85 | TP53 (0.37) | HCRTR2TP53CNR2MAPTALDH1A1 | |
| SCHEMBL6086306 | 0.81 | KMT2A (0.39) | HCRTR2TP53MAPTALDH1A1KMT2A | |
| SCHEMBL6087165 | 0.81 | PDE10A (0.37) | HCRTR2ALDH1A1KDM4E | |
| SCHEMBL6086817 | 0.81 | HPGD (0.43) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL6087446 | 0.81 | HCRTR2 (0.39) | HCRTR2TP53MAPTALDH1A1KMT2A | |
| SCHEMBL6087068 | 0.79 | DAO (0.46) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL6086167 | 0.79 | TLR7 (0.33) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL6087851 | 0.78 | GRIN1 (0.45) | — | |
| SCHEMBL6088257 | 0.78 | NPBWR1 (0.34) | MAPTALDH1A1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |