Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | GABRP | O00591 | 1/20 | 0.61 |
| ▸ | GABRD | O14764 | 1/20 | 0.61 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.61 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.61 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.61 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.61 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.61 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.61 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.61 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.61 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.61 |
| ▸ | GABRE | P78334 | 1/20 | 0.61 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.61 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.61 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.61 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7855224 | 0.87 | MEN1 (0.66) | KMT2AMEN1NPSR1GABRPGABRD | |
| SCHEMBL7846817 | 0.87 | MAPT (0.78) | KMT2AMEN1NPSR1GABRPGABRD | |
| SCHEMBL7838803 | 0.86 | LMNA (0.76) | KMT2AMEN1NPSR1MAPTHPGD | |
| SCHEMBL7851406 | 0.86 | MEN1 (0.68) | KMT2AMEN1NPSR1MAPTHPGD | |
| SCHEMBL7847682 | 0.86 | MEN1 (0.65) | KMT2AMEN1NPSR1MAPTPOLB | |
| SCHEMBL7852539 | 0.86 | MEN1 (0.65) | KMT2AMEN1NPSR1MAPTHPGD | |
| SCHEMBL7839075 | 0.86 | MEN1 (0.65) | KMT2AMEN1NPSR1MAPTHPGD | |
| SCHEMBL7855460 | 0.85 | MEN1 (0.64) | KMT2AMEN1NPSR1MAPTHPGD | |
| SCHEMBL7856952 | 0.84 | KMT2A (0.68) | KMT2AMEN1NPSR1MAPTHPGD | |
| SCHEMBL7854545 | 0.83 | MEN1 (0.61) | KMT2AMEN1NPSR1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140914-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037462-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2000-06-29 | — | — | WO | disclosed |