SCHEMBL7844512

SCHEMBL7844512

C=CCc1cc2c(c(CC=C)c1O)CCC(=O)N2CCCCCCCCCCO

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 6/20 0.34
CHRM4 P08173 6/20 0.34
CHRM5 P08912 6/20 0.34
CHRM1 P11229 6/20 0.34
CHRM3 P20309 6/20 0.34
DRD2 P14416 3/20 0.34
DRD4 P21917 3/20 0.34
DRD3 P35462 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7845505 0.91 KDM4E (0.32)
SCHEMBL7845458 0.90 MGLL (0.41) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL7845311 0.89
SCHEMBL7853643 0.88 KDM4E (0.32)
SCHEMBL7844608 0.88 KDM4E (0.30)
Hydrochloric Acid SCHEMBL7853025 0.87
SCHEMBL7854990 0.84 ALDH1A1 (0.34)
SCHEMBL8662206 0.83
SCHEMBL7854065 0.83 NPSR1 (0.32)
SCHEMBL7853901 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0719258-B1 CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS OTSUKA PHARMA CO LTD (JP) 2001-10-31 EP disclosed
US-5786367-A OXYGEN SCAVENGERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1998-07-28 US disclosed