Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7844442 | 1.00 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL7843450 | 0.92 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL7842482 | 0.92 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL7846026 | 0.91 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL7843488 | 0.91 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL7844808 | 0.89 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL7843264 | 0.89 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL7844958 | 0.89 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL7843757 | 0.89 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL7841076 | 0.89 | PTGS2 (0.66) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1125932-A2 | Substituted thiazoles for the treatment of inflammation | G.D. SEARLE & CO. (US) | 2001-08-22 | — | — | EP | disclosed |
| US-5668161-A | Substituted thiazoles for the treatment of inflammation | G.D. SEARLE & CO. (US) | 1997-09-16 | — | — | US | disclosed |