Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14236812 | 0.86 | GABRA1 (0.54) | GABRA1GABRB2TAAR1CA2ALDH1A1 | |
| SCHEMBL6547971 | 0.82 | GABRA1 (0.45) | GABRA1GABRB2TAAR1CA2ALDH1A1 | |
| SCHEMBL8086373 | 0.82 | TAAR1 (0.48) | USP2TAAR1ALDH1A1TSHRAR | |
| SCHEMBL2844544 | 0.78 | USP2 (0.45) | USP2TAAR1ALDH1A1TSHRAR | |
| SCHEMBL11820855 | 0.76 | AMY1A (0.49) | GABRA1GABRB2CA2ALDH1A1TDP1 | |
| SCHEMBL27500423 | 0.75 | GABRA1 (0.56) | GABRA1GABRB2CA2ALDH1A1TDP1 | |
| SCHEMBL17307162 | 0.75 | GABRA1 (0.55) | GABRA1GABRB2CA2ALDH1A1TDP1 | |
| SCHEMBL3916579 | 0.75 | GABRA1 (0.50) | GABRA1GABRB2TAAR1CA2ALDH1A1 | |
| SCHEMBL26651800 | 0.75 | GABRA1 (0.50) | GABRA1GABRB2TAAR1CA2ALDH1A1 | |
| SCHEMBL9695270 | 0.73 | GABRA1 (0.48) | GABRA1GABRB2CA2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150565-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION bioscience AG (DE) | 2001-11-07 | — | — | EP | claimed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | claimed |