Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846719 | 0.86 | TYMS (0.41) | TYMSFEN1ALDH1A1KDM4EGRIN2B | |
| SCHEMBL6088338 | 0.85 | TYMS (0.44) | TYMSKLKB1ALOX5APALDH1A1MAPT | |
| SCHEMBL7847016 | 0.81 | TYMS (0.46) | TYMSDDR1FEN1ALOX5APALDH1A1 | |
| SCHEMBL7846764 | 0.81 | HSD17B10 (0.37) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7848458 | 0.81 | MAPT (0.36) | DDR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7845884 | 0.81 | GRIN1 (0.36) | ALDH1A1MAPTMEN1KMT2AGRIN2B | |
| SCHEMBL7849696 | 0.80 | HSD17B10 (0.48) | FEN1ALDH1A1MAPTKMT2AGRIN2B | |
| SCHEMBL7844325 | 0.79 | TYMS (0.35) | TYMSDDR1ALDH1A1MAPTMEN1 | |
| SCHEMBL7847748 | 0.78 | MAPT (0.41) | ALDH1A1MAPTMEN1KMT2AP2RX3 | |
| SCHEMBL7848789 | 0.77 | GRIN1 (0.43) | ALDH1A1MEN1KMT2AKDM4EGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |