Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | TPH1 | P17752 | 1/20 | 0.32 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7844325 | 0.89 | TYMS (0.35) | MAPTSMN1; SMN2POLBTP53BACE1 | |
| SCHEMBL7845884 | 0.87 | GRIN1 (0.36) | MAPTSMN1; SMN2LMNARXFP1TP53 | |
| SCHEMBL7846764 | 0.85 | HSD17B10 (0.37) | MAPTSMN1; SMN2LMNATP53BACE1 | |
| SCHEMBL7845907 | 0.83 | MAPT (0.36) | MAPTSMN1; SMN2POLBLMNARXFP1 | |
| SCHEMBL6086074 | 0.83 | MEN1 (0.35) | MAPTSMN1; SMN2POLBLMNARXFP1 | |
| SCHEMBL7846211 | 0.81 | MEN1 (0.36) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 | |
| SCHEMBL7848789 | 0.81 | GRIN1 (0.43) | ALDH1A1MEN1KMT2AKDM4EMAPK10 | |
| SCHEMBL7845229 | 0.81 | TYMS (0.41) | MAPTTP53ALDH1A1MEN1KMT2A | |
| SCHEMBL7849696 | 0.80 | HSD17B10 (0.48) | MAPTPOLBLMNATP53ALDH1A1 | |
| SCHEMBL7847583 | 0.79 | TLR7 (0.32) | MAPTSMN1; SMN2POLBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |