Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836190 | 0.86 | MAPT (0.36) | MAPTALDH1A1LMNAL3MBTL1NPC1 | |
| SCHEMBL6086212 | 0.85 | MAPT (0.42) | MAPTALDH1A1LMNAL3MBTL1NPC1 | |
| SCHEMBL7849696 | 0.81 | HSD17B10 (0.48) | MAPTALDH1A1LMNAL3MBTL1KMT2A | |
| SCHEMBL7848789 | 0.80 | GRIN1 (0.43) | ALDH1A1MEN1KMT2AMAPK10 | |
| SCHEMBL7844325 | 0.79 | TYMS (0.35) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7848458 | 0.79 | MAPT (0.36) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL7845884 | 0.79 | GRIN1 (0.36) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL7836569 | 0.78 | GRIN1 (0.45) | ALDH1A1POLB | |
| SCHEMBL7845229 | 0.78 | TYMS (0.41) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL7846764 | 0.78 | HSD17B10 (0.37) | MAPTALDH1A1LMNAL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |