Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.38 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.38 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.38 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.38 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.38 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.38 |
| ▸ | NDUFB3 | O43676 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851690 | 0.92 | KDM4E (0.43) | CA12CA1CA9KDM4EPOLB | |
| SCHEMBL7852404 | 0.87 | CA12 (0.50) | CA12CA1CA9KDM4EPOLB | |
| SCHEMBL18264075 | 0.76 | CA12 (0.47) | CA12CA1CA9KDM4EPOLB | |
| SCHEMBL11062043 | 0.73 | PDE3B (0.46) | KDM4E | |
| SCHEMBL3825460 | 0.71 | CA12 (0.64) | CA12CA1CA9ALDH1A1MTNR1A | |
| SCHEMBL2797929 | 0.69 | KMT2A (0.48) | ALDH1A1MTNR1AHPGDMAPTTDP1 | |
| SCHEMBL26208699 | 0.68 | NPC1 (0.51) | CA12CA1CA9KDM4EALDH1A1 | |
| SCHEMBL3823460 | 0.68 | CA12 (0.60) | CA12CA1CA9KDM4EALDH1A1 | |
| SCHEMBL7854131 | 0.68 | ADRA2A (0.41) | CA12CA1CA9KDM4EPOLB | |
| SCHEMBL7852544 | 0.68 | ADRA2A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719258-B1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5786367-A | OXYGEN SCAVENGERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0719258-A1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |
| WO-1996002508-A1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-01 | — | — | WO | disclosed |