Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | WDR5 | P61964 | 3/20 | 0.34 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.34 |
| ▸ | ATP4A | P20648 | 2/20 | 0.34 |
| ▸ | ATP4B | P51164 | 2/20 | 0.34 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.34 |
| ▸ | BRS3 | P32247 | 2/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.33 |
| ▸ | ENGASE | Q8NFI3 | 2/20 | 0.33 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.33 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10396242 | 0.84 | AGXT (0.44) | AGXTPDE10AHTTRECQLALDH1A1 | |
| SCHEMBL14853183 | 0.81 | CCR1 (0.39) | AGXTHTTRECQLCCR1CCR5 | |
| SCHEMBL27973179 | 0.80 | LMNA (0.34) | AGXTKMT2AHTTRECQLKDM4E | |
| SCHEMBL29662228 | 0.79 | AGXT (0.42) | AGXTPDE10AHSP90AA1HSP90AB1KMT2A | |
| SCHEMBL94923 | 0.79 | AGXT (0.53) | AGXTPDE10AHSP90AA1HSP90AB1KMT2A | |
| SCHEMBL27916480 | 0.78 | AGXT (0.41) | AGXTHSP90AA1HSP90AB1KMT2ATRAP1 | |
| SCHEMBL28590215 | 0.78 | AGXT (0.41) | AGXTHSP90AA1HSP90AB1KMT2AWDR5 | |
| SCHEMBL29039529 | 0.77 | AGXT (0.52) | AGXTPDE10AHSP90AA1HSP90AB1KMT2A | |
| SCHEMBL29736023 | 0.77 | AGXT (0.52) | AGXTPDE10AHSP90AA1HSP90AB1KMT2A | |
| Hydrochloric Acid SCHEMBL28303939 | 0.77 | AGXT (0.52) | AGXTPDE10AHSP90AA1HSP90AB1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0868423-B1 | METHOD FOR THE SYNTHESIS OF A BENZIMIDAZOLE COMPOUND | ASTRAZENECA AB (SE) | 2001-09-05 | — | — | EP | claimed |