Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | WDR5 | P61964 | 3/20 | 0.35 |
| ▸ | ATP4A | P20648 | 3/20 | 0.35 |
| ▸ | ATP4B | P51164 | 3/20 | 0.35 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | BRS3 | P32247 | 2/20 | 0.34 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.34 |
| ▸ | ENGASE | Q8NFI3 | 2/20 | 0.34 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.34 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28303939 | 0.98 | AGXT (0.52) | AGXTPDE10AHSP90AA1KMT2AWDR5 | |
| SCHEMBL29039529 | 0.98 | AGXT (0.52) | AGXTPDE10AHSP90AA1KMT2AWDR5 | |
| SCHEMBL29736023 | 0.98 | AGXT (0.52) | AGXTPDE10AHSP90AA1KMT2AWDR5 | |
| SCHEMBL16921630 | 0.83 | AGXT (0.46) | AGXTPDE10AHSP90AA1KMT2AWDR5 | |
| SCHEMBL13015490 | 0.81 | AGXT (0.44) | AGXTPDE10AHSP90AA1HSP90AB1MAOA | |
| SCHEMBL9688407 | 0.79 | ACHE (0.39) | AGXTKMT2AMAOAKDM4EALDH1A1 | |
| SCHEMBL7845798 | 0.79 | AGXT (0.52) | AGXTPDE10AHSP90AA1KMT2AWDR5 | |
| SCHEMBL1674711 | 0.77 | AGXT (0.46) | AGXTHSP90AA1KMT2ATRAP1HSP90AB1 | |
| SCHEMBL2740251 | 0.77 | AGXT (0.42) | AGXTMAOAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL192172 | 0.77 | AGXT (0.42) | AGXTHSP90AA1KMT2ATRAP1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273147-A1 | SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2023-11-08 | — | — | EP | claimed |
| CN-112229920-B | Method for detecting potential genotoxic impurities of esomeprazole sodium | 海南中玉药业有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-110317164-B | Preparation method of omeprazole intermediate | 抚州三和医药化工有限公司 | 2022-08-19 | — | — | CN | claimed |
| CN-110041307-B | Preparation method of esomeprazole thioether intermediate | 江苏豪森药业集团有限公司 | 2021-12-17 | — | — | CN | claimed |
| CN-110041307-A | The preparation method of esomeprazole sulfide intermediate | 江苏豪森药业集团有限公司 | 2019-07-23 | — | — | CN | claimed |
| CN-103204841-B | Omeprazole sodium and preparation method | CHENGDU TIANTAISHAN PHARMACEUTICAL CO LTD | 2014-06-25 | — | — | CN | claimed |
| CN-103204841-A | Omeprazole sodium and preparation method | CHENGDU TIANTAISHAN PHARMACEUTICAL CO LTD | 2013-07-17 | — | — | CN | claimed |
| US-20110124634-A1 | BIOACTIVE COMPOUNDS FOR TREATMENT OF CANCER AND NEURODEGENERATIVE DISEASES | PONIARD PHARMACEUTICALS, INC. | 2011-05-26 | — | — | US | claimed |
| EP-2273882-A1 | BIOACTIVE COMPOUNDS FOR TREATMENT OF CANCER AND NEURODEGENERATIVE DISEASES | Poniard Pharmaceuticals, Inc. (US) | 2011-01-19 | — | — | EP | claimed |
| WO-2009139834-A1 | BIOACTIVE COMPOUNDS FOR TREATMENT OF CANCER AND NEURODEGENERATIVE DISEASES | PONIARD PHARMACEUTICALS, INC. (US) | 2009-11-19 | — | — | WO | claimed |
| CN-101486706-A | Omeprazole sodium compound and method for synthesizing the same | JUJUAN DENG (CN) | 2009-07-22 | — | — | CN | claimed |
| EP-1556370-B1 | METHOD FOR THE SYNTHESIS OF A BENZIMIDAZOLE COMPOUND | ASTRAZENECA AB (SE) | 2008-06-11 | — | — | EP | claimed |
| EP-4289425-A2 | NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS D-AMINO ACID OXIDASE (DAAO) INHIBITORS | Tseng, Yufeng, Jane (US) | 2023-12-13 | — | — | EP | disclosed |
| EP-4273147-A1 | SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2023-11-08 | — | — | EP | disclosed |
| EP-4273147-A1 | SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2023-11-08 | — | — | EP | disclosed |
| CN-112229920-B | Method for detecting potential genotoxic impurities of esomeprazole sodium | 海南中玉药业有限公司 | 2022-10-21 | — | — | CN | disclosed |
| EP-0484265-A1 | A process for the preparation of omeprazol | CENTRO GENESIS PARA LA INVESTIGACION, S.L. (ES) | 1992-05-06 | — | — | EP | disclosed |
| EP-0369208-A1 | Process for the preparation of 3,5-dimethyl-4-methoxy pyridine derivatives, and intermediate therefor | Hafslund Nycomed Pharma Aktiengesellschaft (AT) | 1990-05-23 | — | — | EP | disclosed |
| US-4785113-A | 2,4-dichloro-3,5,6-trimethylpyridine | AKTIEBOLAGET HASSLE (SE) | 1988-11-15 | — | — | US | disclosed |
| EP-0226558-A2 | Chemical intermediates and methods for their preparation | Aktiebolaget Hässle (SE) | 1987-06-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124634-A1 | BIOACTIVE COMPOUNDS FOR TREATMENT OF CANCER AND NEURODEGENERATIVE DISEASES | PARK7, BDNF, BACE1 | AGXT 2149/4885PDE10A 1342/4885HSP90AA1 1418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.