⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268825 | 0.92 | — | — | |
| SCHEMBL8178527 | 0.90 | — | — | |
| SCHEMBL563564 | 0.90 | ATP4A (0.80) | — | |
| SCHEMBL9506605 | 0.90 | ATP4A (0.80) | — | |
| SCHEMBL8192240 | 0.89 | — | — | |
| SCHEMBL9165498 | 0.89 | ATP4A (0.79) | — | |
| SCHEMBL9165510 | 0.89 | ATP4A (0.79) | — | |
| Hydrochloric Acid SCHEMBL9264291 | 0.89 | ATP4A (0.79) | — | |
| SCHEMBL8190470 | 0.89 | — | — | |
| SCHEMBL9266013 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143991-A2 | INHIBITORS OF H+K+ -ATPASE | Advanced Medicine, Inc. (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-1999063940-A2 | INHIBITORS OF H+K+-ATPase | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |