Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4897580 | 0.69 | GAA (0.39) | GAAL3MBTL1KDM4EMAPTHSD17B10 | |
| SCHEMBL9327518 | 0.68 | HSD17B10 (0.41) | GAAL3MBTL1KDM4EMAPTTAAR1 | |
| SCHEMBL2398573 | 0.68 | KDM4E (0.44) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL4890988 | 0.67 | NR3C2 (0.45) | HTR1AKDM4ECYP19A1HSD17B10HPGD | |
| SCHEMBL6967987 | 0.66 | HDAC3 (0.39) | MAPTCYP2C9ALDH1A1HDAC3HDAC2 | |
| SCHEMBL14062625 | 0.62 | HTR1A (0.48) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL21971652 | 0.60 | HSD17B10 (0.39) | KDM4ETAAR1HSD17B10HPGDGLA | |
| SCHEMBL31191628 | 0.59 | ALOX5 (0.55) | GAAKDM4ETAAR1HSD17B10HPGD | |
| SCHEMBL1821610 | 0.59 | HSD17B10 (0.42) | GAAL3MBTL1KDM4EMAPTTAAR1 | |
| SCHEMBL5078568 | 0.58 | HTR1A (0.38) | HTR1AHTR7HTR2BTMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656893-B1 | PHOTOCHROMIC OXAZINE COMPOUNDS | RODENSTOCK OPTIK G (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-5801243-A | REACTING A SUBSTITUTED ALDEHYDE WITH A SUBSTITUTED ORTHO-AMINO-HYDROXY AROMATIC COMPOUND | OPTISCHE WERKE G. RODENSTOCK (DE) | 1998-09-01 | — | — | US | disclosed |