Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 7/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846295 | 1.00 | MGLL (0.34) | MGLLFAAHPPARGSSTR4PTGS1 | |
| Hydrochloric Acid SCHEMBL7845734 | 0.99 | MGLL (0.34) | MGLLFAAHPPARGSSTR4PTGS1 | |
| Hydrochloric Acid SCHEMBL7845735 | 0.99 | MGLL (0.34) | MGLLFAAHPPARGSSTR4PTGS1 | |
| SCHEMBL7845045 | 0.86 | MGLL (0.35) | MGLLFAAHPPARG | |
| SCHEMBL7845044 | 0.86 | MGLL (0.35) | MGLLFAAHPPARG | |
| Hydrochloric Acid SCHEMBL7843378 | 0.85 | FAAH (0.34) | MGLLFAAHPPARG | |
| Hydrochloric Acid SCHEMBL7843374 | 0.85 | FAAH (0.34) | MGLLFAAHPPARG | |
| SCHEMBL7844353 | 0.81 | SPHK2 (0.45) | PPARGMAPT | |
| SCHEMBL7844357 | 0.81 | SPHK2 (0.45) | PPARGMAPT | |
| SCHEMBL7836297 | 0.81 | SPHK2 (0.44) | PPARGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767790-B1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | EP | disclosed |
| EP-0767790-A1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-04-16 | — | — | EP | disclosed |
| WO-1995035296-A1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-28 | — | — | WO | disclosed |