Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.55 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843999 | 0.80 | ADORA2A (0.54) | ADORA2AADORA1NHERF1POLBNPC1 | |
| SCHEMBL7834823 | 0.77 | NHERF1 (0.60) | ADORA2AADORA1NHERF1POLBNPC1 | |
| SCHEMBL7845524 | 0.77 | POLB (0.50) | ADORA2AADORA1NHERF1POLBNPC1 | |
| SCHEMBL6818435 | 0.76 | POLB (0.67) | ADORA2AADORA1NHERF1POLBNPC1 | |
| SCHEMBL7845700 | 0.75 | NHERF1 (0.61) | ADORA2AADORA1NHERF1POLBNPC1 | |
| SCHEMBL11946603 | 0.75 | NHERF1 (0.71) | ADORA2AADORA1NHERF1POLBMEN1 | |
| SCHEMBL6670721 | 0.74 | NHERF1 (0.55) | ADORA2AADORA1NHERF1POLBSMN1; SMN2 | |
| SCHEMBL6230550 | 0.73 | NHERF1 (0.68) | ADORA2AADORA1NHERF1POLBSMN1; SMN2 | |
| SCHEMBL6225747 | 0.73 | ADORA2A (0.60) | ADORA2AADORA1NHERF1POLBNPC1 | |
| SCHEMBL6204128 | 0.73 | NHERF1 (0.68) | ADORA2AADORA1NHERF1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140850-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040561-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |