Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843983 | 0.89 | MEN1 (0.41) | MAPK1ALDH1A1 | |
| SCHEMBL7836316 | 0.88 | MAPK1 (0.50) | SMN1; SMN2MAPK1 | |
| SCHEMBL7846036 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL7845399 | 0.87 | MAPK1 (0.49) | SMN1; SMN2MAPK1 | |
| SCHEMBL7835077 | 0.86 | HTT (0.43) | SMN1; SMN2MAPK1HTT | |
| SCHEMBL7846061 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPK1PKMKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7847844 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPK1PKMKDM4EALDH1A1 | |
| SCHEMBL7847024 | 0.77 | — | — | |
| SCHEMBL7847305 | 0.77 | HTT (0.46) | SMN1; SMN2MAPK1PKMHTT | |
| SCHEMBL7847829 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821685-B1 | INDOLE-3-CARBONYL AND INDOLE-3-SULFONYL DERIVATIVES AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LAB (US) | 2001-10-04 | — | — | EP | claimed |