⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847829 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL7843012 | 0.88 | — | — | |
| SCHEMBL7846402 | 0.88 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL7848370 | 0.87 | — | — | |
| SCHEMBL7835347 | 0.83 | CNR1 (0.41) | — | |
| Hydrochloric Acid SCHEMBL7847458 | 0.82 | CNR1 (0.42) | — | |
| SCHEMBL7836609 | 0.80 | MAPK14 (0.40) | — | |
| SCHEMBL7845806 | 0.80 | — | — | |
| SCHEMBL7843983 | 0.79 | MEN1 (0.41) | — | |
| SCHEMBL7498291 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821685-B1 | INDOLE-3-CARBONYL AND INDOLE-3-SULFONYL DERIVATIVES AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LAB (US) | 2001-10-04 | — | — | EP | claimed |