Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846402 | 0.89 | SMN1; SMN2 (0.47) | MAPK1ALDH1A1 | |
| SCHEMBL7847024 | 0.89 | — | — | |
| SCHEMBL7835077 | 0.84 | HTT (0.43) | MAPK1 | |
| SCHEMBL7845147 | 0.81 | CCR5 (0.45) | MEN1KMT2AGLAMAPK1UBE2N | |
| SCHEMBL7835818 | 0.80 | MEN1 (0.44) | MEN1KMT2AGLAMAPK1UBE2N | |
| SCHEMBL7846036 | 0.79 | — | — | |
| SCHEMBL7836316 | 0.78 | MAPK1 (0.50) | MAPK1 | |
| SCHEMBL7498291 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL7845399 | 0.77 | MAPK1 (0.49) | MAPK1 | |
| SCHEMBL7847305 | 0.76 | HTT (0.46) | MAPK1CYP2D6CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821685-B1 | INDOLE-3-CARBONYL AND INDOLE-3-SULFONYL DERIVATIVES AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LAB (US) | 2001-10-04 | — | — | EP | claimed |