Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.47 |
| ▸ | WNT3A | P56704 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15979705 | 0.79 | RAB9A (0.68) | NPC1RAB9AALDH1A1LMNAMEN1 | |
| Methyl Alcohol SCHEMBL27628003 | 0.78 | RAB9A (0.60) | NPC1RAB9AALDH1A1LMNAMEN1 | |
| SCHEMBL9049816 | 0.78 | RAB9A (0.64) | NPC1RAB9AALDH1A1LMNAMEN1 | |
| SCHEMBL6168851 | 0.78 | RAB9A (0.47) | NPC1RAB9AALDH1A1LMNAMEN1 | |
| SCHEMBL7832355 | 0.76 | NPC1 (0.47) | NPC1RAB9AALDH1A1LMNAMEN1 | |
| SCHEMBL7846518 | 0.75 | CES2 (0.43) | NPC1RAB9AMEN1KMT2AHPGD | |
| SCHEMBL7843406 | 0.75 | CTNNB1 (0.47) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL27942177 | 0.74 | DAO (0.47) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL7847516 | 0.73 | RAB9A (0.49) | NPC1RAB9AALDH1A1LMNAMEN1 | |
| SCHEMBL7832513 | 0.73 | CTNNB1 (0.44) | NPC1RAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1125932-A2 | Substituted thiazoles for the treatment of inflammation | G.D. SEARLE & CO. (US) | 2001-08-22 | — | — | EP | disclosed |