Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 4/20 | 0.38 |
| ▸ | BCR | P11274 | 4/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 9/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847267 | 0.88 | ACACB (0.36) | ABL1BCRACACBACACAAAK1 | |
| SCHEMBL7842037 | 0.82 | F2 (0.37) | AAK1 | |
| SCHEMBL7842307 | 0.79 | TRPV1 (0.37) | AAK1BRD9BRD4 | |
| SCHEMBL7846661 | 0.78 | ATR (0.36) | BRD4 | |
| SCHEMBL6366961 | 0.77 | MAPT (0.36) | — | |
| SCHEMBL29850324 | 0.77 | NQO2 (0.43) | BRD4 | |
| SCHEMBL29597551 | 0.77 | AKT1 (0.39) | — | |
| SCHEMBL7229865 | 0.76 | CNR1 (0.43) | CNR1ABL1BCRCYP2A6ACACB | |
| SCHEMBL7450944 | 0.76 | HPGDS (0.45) | — | |
| SCHEMBL7847206 | 0.74 | NQO2 (0.34) | ACACBACACABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157022-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000049015-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-24 | — | — | WO | disclosed |