Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.39 |
| ▸ | TOP2A | P11388 | 5/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7495618 | 0.92 | KCNH2 (0.35) | ADRB2KCNH2TOP2ATOP2B | |
| Trifluoroacetic Acid SCHEMBL7844915 | 0.87 | KCNH2 (0.49) | ADRB2KCNH2TOP2ATOP2BKDM4E | |
| Hydrochloric Acid SCHEMBL7842261 | 0.87 | KCNH2 (0.43) | KCNH2TOP2ATOP2BALDH1A1CHRM2 | |
| SCHEMBL7843567 | 0.85 | ADRB2 (0.40) | ADRB2KCNH2TOP2ATOP2BKDM4E | |
| Hydrochloric Acid SCHEMBL7502049 | 0.83 | KCNH2 (0.34) | KCNH2TOP2ATOP2B | |
| Trifluoroacetic Acid SCHEMBL7842190 | 0.80 | KCNH2 (0.44) | ADRB2KCNH2TOP2ATOP2BKDM4E | |
| Trifluoroacetic Acid SCHEMBL7844276 | 0.79 | KCNH2 (0.43) | ADRB2KCNH2TOP2ATOP2BKDM4E | |
| SCHEMBL7847772 | 0.78 | KCNH2 (0.48) | ADRB2KCNH2TOP2ATOP2BKDM4E | |
| SCHEMBL7502612 | 0.77 | ADRB2 (0.33) | ADRB2 | |
| Trifluoroacetic Acid SCHEMBL7847239 | 0.77 | KCNH2 (0.40) | KCNH2TOP2ATOP2BKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010036941-A1 | Use of 7-(1-aminomethyl-2-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)-quinolonecarboxylic acid and -naphthyridonecarboxylic acid derivatives for the therapy of Helicobacter pylori infections and associated gastroduodenal disorders | PETERSEN UWE (DE) | 2001-11-01 | — | — | US | disclosed |
| US-6288081-B1 | Use of 7-(1-aminomethyl-2-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)-quinolone carboxylic acid and naphthyridone carboxylic acid derivatives for treating Helicobacter pylori infections and the gastroduodenal diseases associated therewith | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010036941-A1 | Use of 7-(1-aminomethyl-2-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)-quinolonecarboxylic acid and -naphthyridonecarboxylic acid derivatives for the therapy of Helicobacter pylori infections and associated gastroduodenal disorders | OXER1, AOC3, PAM | ADRB2 2223/4885KCNH2 3936/4885TOP2A 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.