Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6723476 | 0.72 | SERPINE1 (0.46) | MEN1KMT2ANHERF1THRBALDH1A1 | |
| SCHEMBL6698530 | 0.71 | MEN1 (0.51) | MEN1KMT2AMAPT | |
| SCHEMBL6285021 | 0.71 | L3MBTL1 (0.48) | — | |
| SCHEMBL6286392 | 0.70 | GAA (0.45) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL6699566 | 0.70 | MEN1 (0.48) | MEN1KMT2AMAPT | |
| SCHEMBL6286358 | 0.70 | ABCB1 (0.41) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL6668589 | 0.69 | MAPT (0.61) | MEN1KMT2AMAPT | |
| SCHEMBL6690680 | 0.69 | SMN1; SMN2 (0.44) | KMT2ATHRBALDH1A1MAPT | |
| SCHEMBL6682832 | 0.69 | MMP3 (0.42) | THRBALDH1A1MAPTHPGD | |
| SCHEMBL6703017 | 0.69 | MAPT (0.47) | MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140850-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040561-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |