Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.50 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7838252 | 0.97 | GPR119 (0.50) | GPR119CSF1RKDRACACBKDM1A | |
| SCHEMBL7857235 | 0.90 | GPR119 (0.53) | GPR119CSF1RKDRACACBCHEK2 | |
| SCHEMBL7847387 | 0.89 | GPR119 (0.52) | GPR119CSF1RKDRACACB | |
| Hydrochloric Acid SCHEMBL7847077 | 0.86 | ACHE (0.47) | ACACB | |
| SCHEMBL7837991 | 0.86 | GPR119 (0.59) | GPR119 | |
| SCHEMBL7838157 | 0.83 | HRH3 (0.44) | ACACB | |
| Hydrochloric Acid SCHEMBL7838260 | 0.83 | HRH3 (0.50) | ACACB | |
| Hydrochloric Acid SCHEMBL7847176 | 0.83 | KMT2A (0.46) | ACACBCHEK2 | |
| SCHEMBL7850981 | 0.82 | CHEK2 (0.47) | ACACBCHEK2 | |
| Hydrochloric Acid SCHEMBL7850382 | 0.82 | CXCR4 (0.48) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122252-A1 | NITROGENOUS FUSED HETEROCYCLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-08 | — | — | EP | disclosed |