Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | VNN1 | O95497 | 2/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | CLPP | Q16740 | 1/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7838470 | 0.86 | PKM (0.53) | HSD11B1L3MBTL1MEN1ALDH1A1KMT2A | |
| SCHEMBL7849411 | 0.86 | KDM4E (0.48) | L3MBTL1KDM4EALDH1A1KMT2ACA12 | |
| SCHEMBL984997 | 0.85 | SMN1; SMN2 (0.56) | HSD11B1KDM4EALDH1A1CA12CA1 | |
| SCHEMBL984356 | 0.85 | SMN1; SMN2 (0.56) | HSD11B1KDM4EALDH1A1CA12CA1 | |
| SCHEMBL984354 | 0.85 | SMN1; SMN2 (0.56) | HSD11B1KDM4EALDH1A1CA12CA1 | |
| SCHEMBL984361 | 0.80 | MEN1 (0.52) | HSD11B1L3MBTL1KDM4EMEN1ALDH1A1 | |
| SCHEMBL985136 | 0.80 | MEN1 (0.52) | HSD11B1L3MBTL1KDM4EMEN1ALDH1A1 | |
| SCHEMBL984360 | 0.80 | MEN1 (0.52) | HSD11B1L3MBTL1KDM4EMEN1ALDH1A1 | |
| SCHEMBL7846393 | 0.76 | NPC1 (0.45) | NPC1RAB9AATMHSD11B1L3MBTL1 | |
| SCHEMBL23392434 | 0.75 | AKR1C3 (0.39) | NPC1RAB9AMEN1KMT2AVNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1118612-A1 | Piperazine derivatives possesing nootropic activity | Universita Degli Studi di Firenze (IT) | 2001-07-25 | — | — | EP | claimed |
| EP-1118612-A1 | Piperazine derivatives possesing nootropic activity | Universita Degli Studi di Firenze (IT) | 2001-07-25 | — | — | EP | disclosed |