Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | VNN1 | O95497 | 3/20 | 0.47 |
| ▸ | SPR | P35270 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846882 | 0.86 | NPC1 (0.50) | ALDH1A1KMT2AMEN1VNN1L3MBTL3 | |
| SCHEMBL7849411 | 0.86 | KDM4E (0.48) | ALDH1A1KMT2AVNN1SPRHPGD | |
| SCHEMBL984354 | 0.77 | SMN1; SMN2 (0.56) | ALDH1A1HPGDHSD11B1MGLL | |
| SCHEMBL984356 | 0.77 | SMN1; SMN2 (0.56) | ALDH1A1HPGDHSD11B1MGLL | |
| SCHEMBL984997 | 0.77 | SMN1; SMN2 (0.56) | ALDH1A1HPGDHSD11B1MGLL | |
| SCHEMBL18711619 | 0.76 | SPR (0.40) | KMT2AMEN1VNN1SPR | |
| SCHEMBL10194872 | 0.75 | L3MBTL3 (0.65) | PKMALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL985136 | 0.75 | MEN1 (0.52) | ALDH1A1KMT2AMEN1SPRL3MBTL1 | |
| SCHEMBL984360 | 0.75 | MEN1 (0.52) | ALDH1A1KMT2AMEN1SPRL3MBTL1 | |
| SCHEMBL23392436 | 0.75 | AKR1C3 (0.39) | KMT2AMEN1VNN1SPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1118612-A1 | Piperazine derivatives possesing nootropic activity | Universita Degli Studi di Firenze (IT) | 2001-07-25 | — | — | EP | claimed |
| EP-1118612-A1 | Piperazine derivatives possesing nootropic activity | Universita Degli Studi di Firenze (IT) | 2001-07-25 | — | — | EP | disclosed |