SCHEMBL7846959

SCHEMBL7846959

CCC(C)CCCOc1nsnc1S(C)(=O)=O

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 5/20 0.33
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9038054 0.92
SCHEMBL8445757 0.87 CHRM1 (0.32) CHRM1CA12CA1CA2CA9
SCHEMBL7845517 0.77 CHRM1 (0.35) CHRM1
SCHEMBL8317489 0.75 CA12 (0.41) CHRM1CA12CA1CA2CA9
SCHEMBL9038049 0.71
SCHEMBL6587440 0.65 TSHR (0.56) CA12CA1CA2CA9
SCHEMBL6587448 0.65 TSHR (0.56) CA12CA1CA2CA9
SCHEMBL20326392 0.64 CA12 (0.47) CA12CA1CA2CA9
SCHEMBL8445786 0.62 CHRM1 (0.35) CHRM1
SCHEMBL13056219 0.60 FNTA (0.35) CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1098883-A4 PROCESS FOR PREPARING HETEROCYCLIC COMPOUNDS LILLY CO ELI (US) 2001-11-14 EP disclosed
EP-1098883-A1 PROCESS FOR PREPARING HETEROCYCLIC COMPOUNDS ELI LILLY AND COMPANY (US) 2001-05-16 EP disclosed
WO-1998054151-A1 PROCESS FOR PREPARING HETEROCYCLIC COMPOUNDS ELI LILLY AND COMPANY (US) 1998-12-03 WO disclosed