Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 6/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846990 | 1.00 | ABCC9 (0.53) | ABCC9KCNA5CA12CA1CA9 | |
| SCHEMBL7846762 | 0.77 | ABCC9 (0.49) | ABCC9KCNA5MAPTSMN1; SMN2LMNA | |
| SCHEMBL482335 | 0.73 | ABCC9 (0.64) | ABCC9KCNA5 | |
| SCHEMBL482169 | 0.73 | ABCC9 (0.73) | ABCC9KCNA5MAPT | |
| SCHEMBL10265624 | 0.73 | ABCC9 (0.64) | ABCC9KCNA5 | |
| SCHEMBL482413 | 0.72 | ABCC9 (0.55) | ABCC9KCNA5 | |
| SCHEMBL7836596 | 0.72 | ABCC9 (0.56) | ABCC9MAPTHTTSMN1; SMN2NPSR1 | |
| SCHEMBL7836593 | 0.72 | ABCC9 (0.56) | ABCC9MAPTHTTSMN1; SMN2NPSR1 | |
| SCHEMBL7846555 | 0.71 | KCNA5 (0.43) | ABCC9KCNA5 | |
| SCHEMBL9265483 | 0.70 | KCNA5 (0.53) | ABCC9KCNA5MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747374-B1 | Sulfonamido substituted benzopyran potassium channel activators | BRISTOL MYERS SQUIBB CO (US) | 2001-12-12 | — | — | EP | claimed |
| EP-0747374-B1 | Sulfonamido substituted benzopyran potassium channel activators | BRISTOL MYERS SQUIBB CO (US) | 2001-12-12 | — | — | EP | disclosed |
| EP-0747374-A1 | Sulfonamido substituted benzopyran potassium channel activators | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |