Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.56 |
| ▸ | KCNE1 | P15382 | 10/20 | 0.44 |
| ▸ | KCNQ1 | P51787 | 10/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836593 | 1.00 | ABCC9 (0.56) | ABCC9KCNE1KCNQ1SMN1; SMN2KDM4E | |
| SCHEMBL9200412 | 0.86 | KCNE1 (0.45) | ABCC9KCNE1KCNQ1ALDH1A1MEN1 | |
| SCHEMBL9200392 | 0.86 | KCNE1 (0.45) | ABCC9KCNE1KCNQ1ALDH1A1MEN1 | |
| SCHEMBL9200400 | 0.86 | KCNE1 (0.45) | ABCC9KCNE1KCNQ1ALDH1A1MEN1 | |
| SCHEMBL9200746 | 0.82 | KCNE1 (0.45) | ABCC9KCNE1KCNQ1MEN1KMT2A | |
| SCHEMBL9200759 | 0.82 | KCNE1 (0.45) | ABCC9KCNE1KCNQ1MEN1KMT2A | |
| SCHEMBL9200749 | 0.82 | KCNE1 (0.45) | ABCC9KCNE1KCNQ1MEN1KMT2A | |
| SCHEMBL8003991 | 0.81 | KCNE1 (0.41) | ABCC9KCNE1KCNQ1MEN1KMT2A | |
| SCHEMBL7846865 | 0.79 | ABCC9 (0.49) | ABCC9SMN1; SMN2KDM4EMAPTHTT | |
| SCHEMBL9205841 | 0.78 | ABCC9 (0.54) | ABCC9KCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747374-B1 | Sulfonamido substituted benzopyran potassium channel activators | BRISTOL MYERS SQUIBB CO (US) | 2001-12-12 | — | — | EP | disclosed |
| US-5869478-A | ADMINISTERING AS ANTIISCHEMIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-02-09 | — | — | US | disclosed |