SCHEMBL7847409

SCHEMBL7847409

CCOC(=O)c1cnc2c(OC)cccc2c1Nc1ccccc1C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ATP4A P20648 1/20 0.78
ATP4B P51164 1/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11233459 0.99 ATP4A (0.76) ATP4AATP4B
Sulfuric Acid SCHEMBL11232152 0.96 ATP4A (0.72) ATP4AATP4B
Phosphoric Acid SCHEMBL11241738 0.96 ATP4A (0.72) ATP4AATP4B
SCHEMBL11245876 0.94 ATP4A (0.68) ATP4AATP4B
SCHEMBL11237205 0.93 ATP4A (0.67) ATP4AATP4B
SCHEMBL11233814 0.93 THRB (0.68) ATP4AATP4B
Hydrochloric Acid SCHEMBL11235097 0.93 ATP4A (0.67) ATP4AATP4B
Hydrochloric Acid SCHEMBL11233088 0.92 THRB (0.67) ATP4AATP4B
SCHEMBL11246519 0.92 THRB (0.67) ATP4AATP4B
SCHEMBL11244936 0.92 THRB (0.70) ATP4AATP4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4343804-A 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds A. H. ROBINS COMPANY, INC. (US) 1982-08-10 US claimed
JP-2117663-A None JP disclosed
EP-3538512-B1 NEW ANTHELMINTIC QUINOLINE-3-CARBOXAMIDE DERIVATIVES BAYER ANIMAL HEALTH GMBH (DE) 2021-06-16 EP disclosed
EP-1143991-A2 INHIBITORS OF H+K+ -ATPASE Advanced Medicine, Inc. (US) 2001-10-17 EP disclosed
WO-1999063940-A2 INHIBITORS OF H+K+-ATPase ADVANCED MEDICINE, INC. (US) 1999-12-16 WO disclosed
JP-H02117663-A 4-AMINO-3-QUINOLINECARBOXYLIC ACID AND ITS ESTER A H ROBINS CO INC 1990-05-02 JP disclosed
US-4343804-A 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds A. H. ROBINS COMPANY, INC. (US) 1982-08-10 US disclosed
US-4343804-A 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds A. H. ROBINS COMPANY, INC. (US) 1982-08-10 US disclosed