Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 11/20 | 0.51 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310392 | 0.85 | GLP1R (0.49) | GLP1RCCNT1CDK9MMP1MMP2 | |
| SCHEMBL6307037 | 0.73 | GLP1R (0.42) | GLP1R | |
| SCHEMBL6307860 | 0.73 | GLP1R (0.53) | GLP1R | |
| SCHEMBL6305823 | 0.72 | GLP1R (0.58) | GLP1RCCNT1CDK9MMP1MMP2 | |
| SCHEMBL6304271 | 0.69 | GLP1R (0.54) | GLP1RCCNT1CDK9MMP1MMP2 | |
| SCHEMBL6306880 | 0.68 | GLP1R (0.53) | GLP1RCCNT1CDK9MMP1MMP2 | |
| SCHEMBL6307427 | 0.68 | GLP1R (1.00) | GLP1R | |
| SCHEMBL6310949 | 0.63 | GLP1R (0.73) | GLP1R | |
| SCHEMBL13748764 | 0.61 | — | — | |
| SCHEMBL12124147 | 0.61 | MAPK13 (0.53) | GLP1RMMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147094-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000042026-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-20 | — | — | WO | disclosed |