Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | NQO2 | P16083 | 3/20 | 0.50 |
| ▸ | GLP1R | P43220 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL405486 | 0.86 | TDP1 (0.50) | MAPK13CDK1PIM1DYRK1APIM3 | |
| SCHEMBL29558616 | 0.86 | TDP1 (0.50) | MAPK13CDK1PIM1DYRK1APIM3 | |
| SCHEMBL29512047 | 0.86 | NQO2 (0.52) | MAPK13CDK1PIM1DYRK1APIM3 | |
| SCHEMBL2245783 | 0.86 | NQO2 (0.52) | MAPK13CDK1PIM1DYRK1APIM3 | |
| SCHEMBL2368230 | 0.85 | NQO2 (0.57) | MAPK13CDK1PIM1DYRK1APIM3 | |
| SCHEMBL8686412 | 0.85 | NQO2 (0.62) | MAPK13CDK1PIM1DYRK1APIM3 | |
| SCHEMBL1259520 | 0.81 | HRH4 (0.52) | MAPK13CDK1PIM1DYRK1APIM3 | |
| SCHEMBL1258596 | 0.81 | MMP1 (0.50) | MAPK13CDK1PIM1DYRK1APIM3 | |
| SCHEMBL11805682 | 0.81 | MMP1 (0.44) | MAPK13CDK1PIM1DYRK1APIM3 | |
| 2,3-Dihydroxy-6,7-Dichloroquinoxaline SCHEMBL1259521 | 0.81 | MMP1 (0.50) | MAPK13CDK1PIM1DYRK1APIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8056732-B2 | Microporous polymer material | THE UNIVERSITY OF MANCHESTER (GB) | 2011-11-15 | — | — | US | disclosed |
| US-8056732-B2 | Microporous polymer material | THE UNIVERSITY OF MANCHESTER (GB) | 2011-11-15 | — | — | US | disclosed |
| US-20100304112-A1 | MICROPOROUS POLYMER MATERIAL | THE UNIVERSITY OF MANCHESTER (GB) | 2010-12-02 | — | — | US | disclosed |
| US-20100304112-A1 | MICROPOROUS POLYMER MATERIAL | THE UNIVERSITY OF MANCHESTER (GB) | 2010-12-02 | — | — | US | disclosed |
| US-7690514-B2 | Microporous polymer material | THE UNIVERSITY OF MANCHESTER (GB) | 2010-04-06 | — | — | US | disclosed |
| US-7690514-B2 | Microporous polymer material | THE UNIVERSITY OF MANCHESTER (GB) | 2010-04-06 | — | — | US | disclosed |