Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 14/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6305823 | 0.79 | GLP1R (0.58) | GLP1RMMP1MMP2MMP3CCNT1 | |
| SCHEMBL11805682 | 0.78 | MMP1 (0.44) | GLP1RMMP1MMP2MMP3MAPK13 | |
| SCHEMBL6306880 | 0.74 | GLP1R (0.53) | GLP1RMMP1MMP2MMP3CCNT1 | |
| SCHEMBL9925837 | 0.73 | — | — | |
| SCHEMBL6310392 | 0.71 | GLP1R (0.49) | GLP1RMMP1MMP2MMP3CCNT1 | |
| SCHEMBL6307427 | 0.71 | GLP1R (1.00) | GLP1R | |
| SCHEMBL7847445 | 0.69 | GLP1R (0.51) | GLP1RMMP1MMP2MMP3CCNT1 | |
| SCHEMBL6310949 | 0.69 | GLP1R (0.73) | GLP1R | |
| SCHEMBL12124147 | 0.67 | MAPK13 (0.53) | GLP1RMMP1MMP2MMP3MAPK13 | |
| SCHEMBL6303718 | 0.64 | GLP1R (0.53) | GLP1RMMP1MMP2MMP3MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927214-B1 | Non-peptide GLP-1 agonists | NOVO NORDISK A/S (DK) | 2005-08-09 | — | — | US | disclosed |
| EP-1147094-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000042026-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-20 | — | — | WO | disclosed |