Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7837909 | 0.89 | NPC1 (0.46) | NPC1RAB9AGPR119 | |
| SCHEMBL7847148 | 0.82 | GPR119 (0.51) | NPC1RAB9AGPR119 | |
| SCHEMBL7848790 | 0.81 | NPC1 (0.44) | NPC1RAB9AGPR119KDM1A | |
| SCHEMBL7848718 | 0.81 | NPC1 (0.46) | NPC1RAB9AGPR119ACHEKDM1A | |
| SCHEMBL7838716 | 0.81 | GPR119 (0.45) | NPC1RAB9AGPR119 | |
| SCHEMBL7847275 | 0.79 | ACHE (0.42) | NPC1RAB9AGPR119ACHEKDM1A | |
| SCHEMBL7838242 | 0.79 | CHRM4 (0.44) | NPC1RAB9AGPR119ACHE | |
| SCHEMBL8444749 | 0.76 | KDM4E (0.58) | GPR119 | |
| SCHEMBL10296199 | 0.70 | GPR119 (0.69) | GPR119 | |
| SCHEMBL7847185 | 0.70 | GPR119 (0.54) | NPC1RAB9AGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122252-A1 | NITROGENOUS FUSED HETEROCYCLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-08 | — | — | EP | disclosed |