Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.42 |
| ▸ | GCK | P35557 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6803745 | 0.99 | MAPK14 (0.41) | MAPK14GCKCYP3A4S1PR2RAF1 | |
| SCHEMBL6801883 | 0.94 | MAPK14 (0.46) | MAPK14CYP3A4S1PR2CYP1A2CYP2C9 | |
| SCHEMBL6799622 | 0.87 | JAK2 (0.43) | MAPK14CYP3A4MAPTMAPK1MEN1 | |
| SCHEMBL6801935 | 0.81 | MAPK1 (0.42) | MAPK14GCKMAPTMAPK1MEN1 | |
| SCHEMBL6809060 | 0.81 | MAPK14 (0.42) | MAPK14MAPTMAPK1MEN1ALDH1A1 | |
| SCHEMBL6803640 | 0.80 | MAPK1 (0.42) | GCKCYP3A4S1PR2CYP1A2CYP2C9 | |
| SCHEMBL8079069 | 0.76 | HPGD (0.38) | MAPK14GCKMAPTMAPK1MEN1 | |
| SCHEMBL6803041 | 0.72 | RAB9A (0.48) | S1PR2CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL7683291 | 0.70 | CSNK1A1 (0.60) | MAPK14GCKCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL17895544 | 0.68 | MAOB (0.64) | GCKCYP3A4RAF1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853083-B1 | Pyridylfuran and pyridylthiophene compounds and pharmaceutical use thereof | PFIZER (US) | 2001-09-12 | — | — | EP | claimed |